Preheat the oven to 350°F (175°C).

Lightly grease a loaf pan with cooking spray or line it with parchment paper.

In a large mixing bowl, combine 1 pound ground beef, 1/2 cup almond flour, 1/4 cup grated Parmesan cheese, 1/4 cup finely chopped onion, 2 large eggs, 2 tablespoons Worcestershire sauce, 1 teaspoon garlic powder, 1 teaspoon dried oregano, 1/2 teaspoon salt, and 1/2 teaspoon black pepper; mix by hand until just combined.

Transfer the mixture to the prepared loaf pan and shape it into a loaf.

Spread 1/2 cup sugar-free ketchup over the top of the meatloaf.

Place the loaf pan on a baking sheet and bake for 1 hour or until the internal temperature reaches 160°F (70°C).

Remove from the oven and let the meatloaf rest for 10 minutes before slicing.

Slice the meatloaf and serve warm with your favorite keto sides.